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Two patients had panhypotituitarism and three had partial hypopituitarism. Diabetes insipidus was present in four patients.Among the five patients, the pituitary was enlarged in three,of whom two showed improvement on follow-up MR studies.Three patients had a thickened stalk,which improved on subsequent examinations.In all nine dynamic studies,the enhancement time of the whole pituitary was delayed to over 90 seconds,even though five of the nine conventional,simultaneously performed MR studies showed a normal pituitary.The peak time of posterior pituitary enhancement in the first dynamic study was also delayed in all patients(from 60 to 120 seconds).In two patients,normal early enhancement of the posterior pituitary was identified on initial studies but not on subsequent studies. Dynamic MR imaging can display an abnormality of the hypophysial vasculature even if the pituitary disease is seen to regress on the conventional MR study.The delay or even the lack of early enhancement of the posterior pituitary in lymphocytic hypophysitis may be due to secondary inflammatory changes. |
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diabetes insipidus
gadolinium
hypopituitarism
lymphoid adenohypophysitis
MRI
MRI,abnormal
MRI,contrast enhanced
MRI,serial
neuroendocrinology
pituitary
pituitary stalk,lesion of
pituitary,enlargement
pituitary,lesion of
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